Breakthrough discovery could pave the way for the development of the world’s first pharmacological interventions against hearing loss

Professor UEYAMA Takehiko (Biosignal Research Center, Kobe University) and the inner ear research group (Kyoto Prefectural University of Medicine) have identified the cell types in the inner ear cochlea (*1) responsible for the production of superoxide (Nox3*2-expressing cells).

These results are expected to contribute towards the development of the world’s first drug-based treatment for hearing loss. Future treatments could involve removing reactive oxygen species from the cochlea, suppressing their production, or the development of Nox3 inhibitors.

These research results were published in the official journal of the Society for Neuroscience ‘Journal of Neuroscience’ on April 12, 2021.


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